MICROVASCULAR IMPAIRMENT IN PATIENTS WITH CEREBRAL SMALL VESSEL DISEASE ASSESSED WITH ARTERIAL SPIN LABELING MAGNETIC RESONANCE IMAGING: A PILOT STUDY

In this pilot study, we investigated microvascular impairment in patients with cerebral small vessel disease (CSVD) using non-invasive arterial spin labeling (ASL) magnetic resonance imaging (MRI).This method enabled us to measure the perfusion parameters, cerebral blood flow (CBF), and arterial transit time (ATT), and the effective T1-relaxation t

Abstract Background Process intensification is a major hurdle in pharmaceutical process scale-up.Solvent removal strategies have limited the effectiveness of the overall stability of pharmaceutical formulations.The main aim of present review article is to focus on the use of the freeze-drying process in pharmaceuticals, biopharmaceuticals and nanod

Driven by the pain points of the organic food supply chain, which has been plagued by counterfeiting and difficulties in pursuing accountability, this paper investigates a secondary organic food supply chain consisting of suppliers and retailers and establishes two supply chain models under the traditional model and in the blockchain traceability c

Trichobezoar is caused by hair ingestion that accumulates in the gastrointestinal tract.It is associated with psychiatric disorders.Occasionally, the hairs invade through pylorus and cause obstruction, which is known as Lip Cream Rapunzel Syndrome.A 9-year-old girl was admitted with signs of intestinal obstruction and a lump at her left side abdome

Abstract Background Restless legs syndrome (RLS) is a chronic disorder with substantial impact on quality of life similar to that seen in diabetes mellitus or osteoarthritis.Little is known about the psychological characteristics of RLS patients although psychological BRAIN B-12 1000MCG factors may contribute to unfavourable treatment outcome.Metho